Therapeutic Potential of an Anti-PLAC1 Antibody-Drug Conjugate in a Mouse Model of Human Breast Cancer
Iran J Immunol
.
2025 Sep 30;22(3):192-206.
doi: 10.22034/iji.2025.106670.3019.
Authors
Jafar Mahmoudian
1
2
,
Roya Ghods
3
4
,
Mahmood Jeddi-Tehrani
2
,
Nassim Ghaffari-Tabrizi-Wizsy
5
,
Mohammad Reza Nejadmoghaddam
6
,
Ramin Ghahremanzadeh
6
,
Seyed Nasser Ostad
1
7
,
Amir-Hassan Zarnani
8
9
Affiliations
1
Nanotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
2
Monoclonal Antibody Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
3
Oncopathology Research Center, Iran University of Medical Sciences, Tehran, Iran.
4
Department of Molecular Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran.
5
SFL Chicken CAM Lab, Institute of Pathophysiology and Immunology, Medical University of Graz, Graz, 8010, Austria.
6
Nanobiotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
7
Department of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
8
Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
9
Reproductive Immunology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
PMID:
41025819
DOI:
10.22034/iji.2025.106670.3019
No abstract available
Keywords:
Breast cancer; CAM; Placenta-specific 1 (PLAC1); SN38; Tumorigenesis.