Tracing cell fates in embryos

Ying Zhang; Qi Chen

doi:10.7554/eLife.108962

Tracing cell fates in embryos

Elife. 2025 Oct 1:14:e108962. doi: 10.7554/eLife.108962.

Authors

Ying Zhang¹, Qi Chen²

Affiliations

¹ The Key Laboratory of Cell Proliferation and Regulation Biology, Ministry of Education, College of Life Sciences, Beijing Normal University, Beijing, China.
² Molecular Medicine Program, Department of Human Genetics, Division of Urology, Department of Surgery, University of Utah School of Medicine, Salt Lake City, United States.

Abstract

Differences in the activity of an enzyme called CARM1 influence the timing of blastomere polarization and whether they become part of the embryo or the placenta.

Keywords: cell fate; developmental biology; mouse; mouse embryo development; polarity; preimplantation development.

Publication types

Editorial

MeSH terms

Animals
Blastomeres* / cytology
Blastomeres* / physiology
Cell Lineage*
Embryo, Mammalian* / cytology
Female
Placenta

Grants and funding

R35 ES035015/ES/NIEHS NIH HHS/United States