Factors influencing catheter-related infections in peritoneal dialysis patients: a meta-analysis

PeerJ. 2025 Sep 29:13:e20063. doi: 10.7717/peerj.20063. eCollection 2025.

Abstract

Objective: Systematic analysis of factors influencing catheter-related infections in patients undergoing peritoneal dialysis.

Methods: A computerized search of Chinese and English databases was conducted to identify the factors affecting catheter-related infections in patients undergoing peritoneal dialysis. Studies with a search period from inception to July 31, 2024 were retrieved. Two researchers independently screened the literature using inclusion and exclusion criteria, and data extraction and quality assessments were performed. Meta-analysis was performed using RevMan5.4 and Stata software.

Results: In total, 13 studies were included and meta-analysis revealed that comorbid diabetes mellitus, insecure catheter fixation, dialysis duration >2 years, body mass index >20 kg/m2, mechanical strain, lack of proper care, irregular caregivers, and history of catheter pulling (P < 0.05) were the influencing factors contributing to the incidence of catheter-related infections in patients undergoing peritoneal dialysis.

Conclusions: Clinicians should pay close attention to these influencing factors and provide targeted preventive measures to prevent catheter-related infections.

Keywords: Catheter-related infections; Chronic kidney disease; Evidence-based nursing; Meta-analysis; Peritoneal dialysis.

Publication types

  • Meta-Analysis
  • Systematic Review

MeSH terms

  • Catheter-Related Infections* / epidemiology
  • Catheter-Related Infections* / etiology
  • Catheters, Indwelling / adverse effects
  • Humans
  • Peritoneal Dialysis* / adverse effects
  • Risk Factors