Clinical Outcomes of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Based on Hospital Admission Type

Cutis. 2025 Aug;116(2):70-73. doi: 10.12788/cutis.1248.

Abstract

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) require prompt hospital admission with access to inpatient dermatologic care. Delayed admission of 5 days or more has been associated with increases in overall mortality, bacteremia, intensive care unit (ICU) admission, and length of stay. In this study, we analyzed the association between admission pathway and clinical outcomes of patients with SJS/TEN. A single-center retrospective chart review was performed at Atrium Health Wake Forest Baptist Medical Center (AHWFBMC)(Winston-Salem, North Carolina), to assess demographics, comorbidities, outside hospital transfer status, complications during admission, inpatient length of stay in days, interventions received, and site of admission: directly from AHWFBMC emergency department or transferred from an outside hospital.

MeSH terms

  • Adult
  • Aged
  • Emergency Service, Hospital / statistics & numerical data
  • Female
  • Hospitalization* / statistics & numerical data
  • Humans
  • Intensive Care Units / statistics & numerical data
  • Length of Stay / statistics & numerical data
  • Male
  • Middle Aged
  • North Carolina
  • Patient Admission* / statistics & numerical data
  • Retrospective Studies
  • Stevens-Johnson Syndrome* / complications
  • Stevens-Johnson Syndrome* / mortality
  • Stevens-Johnson Syndrome* / therapy