Premorbid Metabolic Syndrome Is Associated with the Hypoinflammatory Phenotype in Acute Respiratory Distress Syndrome and Sepsis
Am J Respir Crit Care Med
.
2025 Dec;211(12):2399-2401.
doi: 10.1164/rccm.202503-0596RL.
Authors
Avery M Bogart
1
2
,
Sarah N Obeidalla
3
,
Rombout B E van Amstel
4
,
Olaf Cremer
4
5
,
Lieuwe D J Bos
4
,
Brian Bartek
6
,
Pratik S Sinha
6
,
Carolyn S Calfee
7
8
,
V Eric Kerchberger
9
3
,
Lorraine B Ware
1
3
;
MARS Consortium
Collaborators
MARS Consortium
:
Friso M de Beer
,
Lieuwe D J Bos
,
Gerie J Glas
,
Arie J Hoogendijk
,
Roosmarijn T M van Hooijdonk
,
Janneke Horn
,
Mischa A Huson
,
Laura R A Schouten
,
Marcus J Schultz
,
Brendon P Scicluna
,
Marleen Straat
,
Tom van der Poll
,
Lonneke A van Vught
,
Luuk Wieske
,
Maryse A Wiewel
,
Esther Witteveen
,
Marc J M Bonten
,
Olaf M Cremer
,
David S Y Ong
,
Jos F Frencken
,
Peter M C Klein Klouwenberg
,
Maria E Koster-Brouwer
,
Kirsten van de Groep
,
Diana M Verboom
Affiliations
1
Department of Pathology, Microbiology, and Immunology.
2
Vanderbilt University School of Medicine, Nashville, Tennessee.
3
Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
4
Department of Intensive Care Medicine, Amsterdam University Medical Center, Locatie Amsterdam Medical Center, Amsterdam, the Netherlands.
5
Department of Intensive Care, University Medical Center Utrecht, Utrecht, the Netherlands.
6
Division of Clinical and Translational Research, Department of Anesthesia, Washington University in St Louis, St. Louis, Missouri; and.
7
Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine and.
8
Department of Anesthesia, University of California, San Francisco, San Francisco, California.
9
Department of Biomedical Informatics, and.
PMID:
41072401
PMCID:
PMC12700243
DOI:
10.1164/rccm.202503-0596RL
No abstract available
Publication types
Letter
Grants and funding
HL140026/HI/NHLBI NIH HHS/United States
F30HL170483/HI/NHLBI NIH HHS/United States
HL168412/HI/NHLBI NIH HHS/United States
R35 GM142992/GM/NIGMS NIH HHS/United States
HL158906/HI/NHLBI NIH HHS/United States