Through collecting the existing clinical evidences on acupuncture and moxibustion for urticaria, the distribution of evidence in this field was mapped. A systematic search of Chinese and English literature was conducted in CNKI, Wanfang, VIP, SinoMed, PubMed, EMbase, and Cochrane Library for treatment of urticaria with acupuncture and moxibustion, published up to December 31, 2023 since inception of each database. The research status in this field was summarized using an evidence mapping approach, and methodological quality was assessed. A total of 323 randomized controlled trials (RCTs) and 22 systematic reviews were included. The number of studies on acupuncture and moxibustion for urticaria has been increasing, with a significant rise in recent years. In most RCTs, the study scale was small, and the subjects focused on chronic spontaneous urticaria in adolescents and middle-aged adults, aged 14 to 60 years. Regarding the intervention measures, the single therapy of acupuncture and moxibustion was predominant such as acupoint injection, acupoint embedding thread, and filiform needling. In acupuncture with filiform needles, the commonly used acupoints were Quchi (LI11), Xuehai (SP10), Sanyinjiao (SP6), Zusanli (ST36) and Hegu (LI4). The main outcome measures referred to effectiveness rate, score of disease severity, recurrence rate, laboratory indexes, and score of quality of life; and the short-term effect was evaluated specifically. The overall methodological quality of the included studies was relatively low. It is suggested that the future research should focus on large-scale, multi-center, high-quality clinical trials, optimize the protocols for acupuncture and moxibustion intervention, standardize the outcomes, and draw the attention to the evaluation of long-term efficacy, so as to provide clinical evidences of high certainty for urticaria treated with acupuncture and moxibustion.
搜集针灸治疗荨麻疹临床研究的现有证据，展示该领域证据分布。系统检索中国期刊全文数据库（CNKI）、万方数据知识服务平台（Wanfang）、维普资讯中文期刊服务平台（VIP）、中国生物医学文献数据库（SinoMed）、PubMed、EMbase、Cochrane Library自建库至2023年12月31日所收录的针灸治疗荨麻疹的中英文文献。以证据图的形式总结该领域研究现状，并进行方法学质量评价。共纳入323篇随机对照试验（RCT）和22篇系统评价文献。针灸治疗荨麻疹的研究数量呈上升趋势且近年显著增加。大多RCT研究规模较小，研究对象主要集中在14~60岁青少年与中年人的慢性自发性荨麻疹人群。干预措施以单一针灸疗法居多，包括穴位注射、穴位埋线、毫针刺等，其中毫针刺法常用腧穴为曲池、血海、三阴交、足三里、合谷等。结局指标主要集中在有效率、疾病严重程度评分、复发率、实验室指标、生活质量评分，且以短期疗效评价为主。总体纳入文献的方法学质量评价较低。未来应开展大样本、多中心、高质量的临床研究，优化针灸干预方案，规范结局指标体系，关注远期疗效评价，为针灸治疗荨麻疹提供高级别的临床证据。.
Keywords: acupuncture and moxibustion therapy; evidence map; randomized controlled trials (RCT); systematic review; urticaria.