ObjectiveTo examine the feasibility of a home-based high-intensity balance training programme (HBBT-MS) and its preliminary efficacy in individuals with multiple sclerosis (MS).DesignA single-group pretest-posttest design.SettingCommunity.SubjectsTwenty-eight individuals with MS (23 female (82%); mean age: 55.2 ± 11.9).InterventionsParticipants performed the program for 30 minutes per session, 3 days per week for 12 weeks, with the support of a family member to ensure safety while maintaining a high balance challenge.Main measuresFeasibility was assessed using four domains of process, resources, management, and scientific outcomes. Physical function (static balance, lower-extremity function, and mobility), dual-tasking, cognitive function (processing speed, verbal memory, and visuospatial memory), and self-reported outcomes (fatigue, dual-task difficulty, ambulation difficulty, and fear of falling) were assessed at baseline and post-intervention.ResultsTwenty-six out of 28 participants completed both the pretest and posttest (adherence rate: 92.9%). No severe adverse events attributed to this program were reported. There were significant and small-to-medium improvements in static balance (d = 0.74, p < 0.001), lower-extremity function (d = 0.70, p < 0.001), and mobility (d = 0.34, p = 0.004), with no improvement observed in dual-tasking. Participants showed significant and medium improvement in processing speed (d = 0.71, p = 0.007) and visuospatial memory (d = 0.55, p = 0.22), but not verbal memory (d = 0.02, p = 0.22). We observed significant improvements in all self-reported outcomes.ConclusionsThe HBBT-MS was feasible, safe, and acceptable. Further evaluation using a controlled design is warranted to examine the effectiveness of the programme.Clinical trial registration: clinicaltrials.gov; NCT06412003.
Keywords: Cognition; exercise; mobility; rehabilitation; telehealth.