1 Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT 06520, USA; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.
2 Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT 06520, USA; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA; Yale Center for RNA Science and Medicine, New Haven, CT 06520, USA; Yale Cooperative Center of Excellence in Hematology, New Haven, CT 06520, USA; Yale Cancer Center, New Haven, CT 06520, USA. Electronic address: jun.lu@yale.edu.
A new function of glycosylated RNAs has been discovered by Graziano et al.1 in which the glycosylation of RNA molecules shields acp³U RNA modification from triggering innate immune responses.