USP25 in genetic generalized epilepsy: a gene under scrutiny
Brain
.
2026 Feb 7;149(2):e16-e18.
doi: 10.1093/brain/awaf406.
Authors
Maryam Erfanian Omidvar
1
2
,
Jill R Murrell
3
,
Anna J Prentice
4
5
6
,
Ingo Helbig
4
5
6
7
8
9
,
Holger Lerche
1
,
Patrick May
2
;
Epi25 Collaborative
Collaborators
Epi25 Collaborative
:
Siwei Chen
,
Zaid Afawi
,
Quratulain Zulfiqar Ali
,
Elisabetta Amadori
,
Alison Anderson
,
Danielle M Andrade
,
Grazia Annesi
,
Ganna Balagura
,
Simona Balestrini
,
Carmen Barba
,
Larry W Baum
,
Tobias H Baumgartner
,
Betül Baykan
,
Felicitas Becker
,
Caitlin A Bennett
,
Ahmad Beydoun
,
Francesca Bisulli
,
Ingo Borggräfe
,
Christian Bosselmann
,
Russell J Buono
,
Robyn M Busch
,
Laura Canafoglia
,
Barbara Castellotti
,
Gianpiero L Cavalleri
,
Felecia Cerrato
,
I-Jun Chou
,
Seo-Kyung Chung
,
Andrew J Cole
,
Patrick Cossette
,
Chris Cotsapas
,
Chantal Depondt
,
Orrin Devinsky
,
Dennis J Dlugos
,
Viola Doccini
,
Colin Ellis
,
Leon Epstein
,
Meghan Evans
,
Annika Faucon
,
Lisa Ferguson
,
Thomas N Ferraro
,
Martha Feucht
,
Mark Fitzgerald
,
Francesco Fortunato
,
Jacqueline A French
,
Elena Freri
,
Monica Gagliardi
,
Alica Goldman
,
David B Goldstein
,
Tiziana Granata
,
Renzo Guerrini
,
Kevin Haas
,
Erin L Heinzen
,
Ingo Helbig
,
Henrike Heyne
,
Olivia Hoeper
,
Luciana Midori Inuzuka
,
Lara Jehi
,
Reetta Kälviäinen
,
Symon M Kariuki
,
Jean Khoury
,
Karl Martin Klein
,
Gerhard Kluger
,
Susanne Knake
,
Andreas Koupparis
,
Ioanna Kousiappa
,
Roland Krause
,
Martin Krenn
,
Heinz Krestel
,
Gerhard Kurlemann
,
Angelo Labate
,
Austin Lacey
,
Charlotte Lawthom
,
Stephanie L Leech
,
Johannes R Lemke
,
Holger Lerche
,
Gaetan Lesca
,
Costin Leu
,
David Lewis-Smith
,
Calwing Liao
,
Laura Licchetta
,
Daniel H Lowenstein
,
Francesca Madia
,
Stefania Magri
,
Patrick May
,
Christopher M McGraw
,
Davide Mei
,
John J Millichap
,
Raffaella Minardi
,
Lorenzo Muccioli
,
Hiltrud Muhle
,
Karen Müller-Schlüter
,
Wassim Nasreddine
,
Bernd A Neubauer
,
Charles R J C Newton
,
Terence J O'Brien
,
Çiğdem Özkara
,
Savvas S Papacostas
,
Elena Parrini
,
Manuela Pendziwiat
,
William O Pickrell
,
Dalila Pinto
,
Annapurna Poduri
,
Francesca Ragona
,
Mark I Rees
,
Sylvain Rheims
,
Antonella Riva
,
Enrique Rojas
,
Ilaria Sammarra
,
Christoph J Schankin
,
Ingrid E Scheffer
,
Susanne Schubert-Bast
,
Andreas Schulze-Bonhage
,
Beth R Shiedley
,
Sanjay M Sisodiya
,
Kathryn R Sparks
,
Ulrich Stephani
,
Pasquale Striano
,
Adam Strzelczyk
,
Rainer Surges
,
Toshimitsu Suzuki
,
Mariagrazia Talarico
,
Michael E Talkowski
,
George A Tanteles
,
Paolo Tinuper
,
Marian Todaro
,
Pınar Topaloglu
,
Meng-Han Tsai
,
Birute Tumiene
,
Dilsad Turkdogan
,
Algirdas Utkus
,
Luc Valton
,
Andreas van Baalen
,
Annalisa Vetro
,
Ryan G Wagner
,
Yvonne G Weber
,
Sarah Weckhuysen
,
Samuel Wiebe
,
Stefan Wolking
,
Randi von Wrede
,
Zuhal Yapıcı
,
Felix Zahnert
,
Federico Zara
,
Gábor Zsurka
,
Benjamin M Neale
,
Samuel F Berkovic
Affiliations
1
Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen 72076, Germany.
2
Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux 4367, Luxembourg.
3
Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
4
Division of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
5
Department of Biomedical and Health Informatics (DBHi), Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
6
The Epilepsy NeuroGenetics Initiative (ENGIN), Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
7
Department of Neurology, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA 19104, USA.
8
Department of Neuropediatrics, University Medical Center Schleswig-Holstein, Christian-Albrechts-University, Kiel 24105, Germany.
9
Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel 24105, Germany.
PMID:
41144622
DOI:
10.1093/brain/awaf406
No abstract available
Publication types
Editorial
Comment
Grants and funding
Centers for Common Disease Genomics (CCDG)
National Human Genome Research Institute (NHGRI)
National Heart, Lung, and Blood Institute (NHLBI)
UM1 HG008895/HG/NHGRI NIH HHS/United States
5U01HG009088-02/HG/NHGRI NIH HHS/United States
NH/NIH HHS/United States
1R03NS108145-01/'Epi25 Clinical Phenotyping R03' National Institutes of Health
FOR-2715/'Epi25 Clinical Phenotyping R03' National Institutes of Health
German Research Foundation
DFG LE1030/16-2/Luxembourg Fond National de la Recherche
FNR INTER/DFG/21/16394868/Luxembourg Fond National de la Recherche