Breathing Easier: Optimizing Pulmonary Health in Children With Sickle Cell Disease

Pediatr Rev. 2025 Nov 1;46(11):633-639. doi: 10.1542/pir.2024-006659.

Abstract

Pulmonary care in children with sickle cell disease is paramount to quality of life and health. Early identification and treatment of common respiratory conditions such as asthma and sleep-disordered breathing can help decrease morbidity in this population. Understanding how respiratory comorbidities can lead to end-organ damage and acute chest syndrome can lead to more proactive care when the patient is at health baseline. Patient access to specialty care may be limited, but robust primary care can lead to life-saving interventions. Pediatricians, pediatric pulmonologists, and pediatric hematologists can partner together to deliver multidisciplinary care that addresses medical, ethical, and social considerations for a population of children that deserves comprehensive care.

Publication types

  • Review

MeSH terms

  • Acute Chest Syndrome
  • Anemia, Sickle Cell* / complications
  • Anemia, Sickle Cell* / therapy
  • Asthma / diagnosis
  • Asthma / etiology
  • Asthma / therapy
  • Child
  • Humans
  • Quality of Life
  • Sleep Apnea Syndromes / etiology
  • Sleep Apnea Syndromes / therapy