Cellular responses to methylcholanthrene; the role of benzpyrene hydroxylase in the binding of polycyclic hydrocarbon to cytosol macromolecules in fetal rat liver explants

MeSH terms

• Animals
• Benzopyrenes
• Carbon Isotopes
• Chromatography, Gel
• Cytoplasm / drug effects
• Cytoplasm / metabolism
• Dose-Response Relationship, Drug
• Kinetics
• Ligands
• Liver / cytology
• Liver / drug effects*
• Liver / enzymology
• Liver / metabolism
• Male
• Methylcholanthrene / metabolism
• Methylcholanthrene / pharmacology*
• Mixed Function Oxygenases / antagonists & inhibitors
• Mixed Function Oxygenases / physiology*
• Organ Culture Techniques
• Polycyclic Compounds / metabolism*
• Polycyclic Compounds / pharmacology
• Protein Binding
• RNA / metabolism
• Rats
• Subcellular Fractions / metabolism
• Ultrafiltration