Muscle Mass, Fragility, Weight Loss, and Cancer Treatment

Timothy P Dougherty; Rainer J Klement; Colin E Champ

doi:10.1001/jamaoncol.2025.4521

Muscle Mass, Fragility, Weight Loss, and Cancer Treatment

JAMA Oncol. 2025 Dec 1;11(12):1422-1423. doi: 10.1001/jamaoncol.2025.4521.

Authors

Timothy P Dougherty^{1

2}, Rainer J Klement³, Colin E Champ^{1

2}

Affiliations

¹ Department of Radiation Oncology, Allegheny Health Network, Pittsburgh, Pennsylvania.
² Allegheny Health Network Cancer Institute, Exercise Oncology and Resilience Center, Pittsburgh, Pennsylvania.
³ Department of Radiation Oncology, Leopoldina Hospital, Schweinfurt, Germany.

PMID: 41196575
DOI: 10.1001/jamaoncol.2025.4521

No abstract available

Plain language summary

This Viewpoint discusses adverse effects associated with pharmacologic treatment of patients with cancer and overweight or obesity and emphasizes the importance of lifestyle modifications.