Considerations in the Diagnosis and Management of Bronchiectasis in Older Adults

Clin Geriatr Med. 2025 Nov;41(4):539-551. doi: 10.1016/j.cger.2025.07.006. Epub 2025 Aug 7.

Abstract

Bronchiectasis is characterized by chronic airway inflammation and scarring resulting in cough and recurrent respiratory infections. It is strongly associated with aging. Risk factors include impaired mucociliary clearance, structural lung and chest wall changes, aspiration, and comorbidities such as chronic obstructive pulmonary disease. Radiographic bronchiectasis is a common incidental finding in older adults; clinical diagnosis of bronchiectasis requires characteristic symptoms. Management involves both nonpharmacologic strategies (airway clearance, pulmonary rehabilitation) and pharmacologic therapies (antibiotics, inhaled treatments). Shared decision-making about treatment is essential and should take into account impact on quality of life, functional ability, cognition, comorbid conditions, and risks of polypharmacy.

Keywords: Aging; Bronchiectasis; Elderly; Older adults.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Bronchiectasis* / diagnosis
  • Bronchiectasis* / therapy
  • Humans
  • Quality of Life
  • Risk Factors

Substances

  • Anti-Bacterial Agents