Oncogenes out of context: Cancer genes break free from the regulatory constraints of chromosomes

Science. 2025 Nov 13;390(6774):686. doi: 10.1126/science.aec9588. Epub 2025 Nov 13.

Author

King L Hung^{1

2

3}

Affiliations

¹ Department of Neuroscience, Scripps Research, La Jolla, CA, USA.
² Department of Dermatology, Stanford University, Stanford, CA, USA.
³ Department of Genetics, Stanford University, Stanford, CA, USA.

PMID: 41232000
DOI: 10.1126/science.aec9588

Abstract

Cancer genes break free from the regulatory constraints of chromosomes.

MeSH terms

Animals
Chromosomes, Human* / genetics
Gene Expression Regulation, Neoplastic*
Genes, Neoplasm*
Humans
Neoplasms* / genetics
Oncogenes*