An osteoporosis course as a separate component of problem-based learning

PLoS One. 2025 Nov 14;20(11):e0336915. doi: 10.1371/journal.pone.0336915. eCollection 2025.

Abstract

Study groups and methods: Study group I was comprised of 25 fourth-year students who successfully completed the Elective Osteoporosis Course I (focused on pathophysiology, diagnostics, and pharmacological treatment), while control group I was comprised of 25 fifth-year students who successfully completed only all required fourth- and fifth-year courses, but did not participate in the elective Osteoporosis I course. Study group II was comprised of 27 fourth-year students who successfully completed the Elective Osteoporosis Course II (focused on treatment of osteoporotic fractures), while control group II was comprised of 24 sixth-year students who were preparing for final exams in surgical disciplines, but did not participate in the Elective Osteoporosis Course II. The groups were compared using a linear regression model with robust estimation of standard errors using Stata 13.1. A p-value < 0.05 was considered statistically significant.

Results: Study Group I scored, on average, 6.7 points higher than Control Group I on the multiple-choice test (scale -16 to +21). Study Group II scored, on average, 3.5 points higher than Control Group II on the multiple-choice test (scale -21 to +28). Both differences were statistically significant (p < 0.001, R2 = 0.64, 95% CI: 5.2-8.1; p = 0.006, R2 = 0.15, 95% CI: 1.1-5.9; respectively).

Conclusion: Results demonstrated a greater understanding in students who participated in problem-based learning medical studies relative to those who completed only the mandatory curriculum.

MeSH terms

  • Curriculum
  • Educational Measurement
  • Female
  • Humans
  • Male
  • Osteoporosis* / diagnosis
  • Osteoporosis* / therapy
  • Problem-Based Learning* / methods