Dual dysregulation of TNF/interferon signaling and classical monocytes are implicated in Reactive Infectious Mucocutaneous Eruptions

JCI Insight. 2025 Nov 20:e194642. doi: 10.1172/jci.insight.194642. Online ahead of print.

Authors

Zhehao Tan¹, Gio Wu¹, Daniela Salgado Figueroa¹, Paramita Dutta², Zachary Jaeger³, Marissa Mazurie³, David Schairer³, Dawn Eichenfield³, Wynnis L Tom³, Lauren Galli⁴, Lawrence Eichenfield³, Bob Geng⁴, Brian Hinds³, Hal M Hoffman¹, Lori Broderick¹, Ben Croker¹, Ferhat Ay¹, Reid Oldenburg³

Affiliations

¹ Department of Pediatrics, University of California San Diego, La Jolla, United States of America.
² Centers for Autoimmunity, Inflammation and Cancer Immunotherapy, La Jolla Institute for Immunology, La Jolla, United States of America.
³ Department of Dermatology, University of California San Diego, La Jolla, United States of America.
⁴ Division of Allergy and Immunology, Rady Children's Hospital, San Diego, United States of America.

PMID: 41264360
DOI: 10.1172/jci.insight.194642

No abstract available

Keywords: Cytokines; Dermatology; Immunology; Inflammation; Skin; Transcriptomics.