[Management of patients with aortic stenosis and concomitant mitral regurgitation: diagnostic challenges and therapeutic strategies in the era of percutaneous interventions]

Abstract

Severe aortic stenosis and mitral regurgitation frequently coexist and pose significant diagnostic and therapeutic challenges. The hemodynamic interplay between these two valvular diseases can obscure the accurate assessment of each lesion, necessitating an advanced understanding of flow dynamics and cardiac remodeling. This review explores the complex relationship between aortic stenosis and mitral regurgitation, highlighting pathophysiological mechanisms, diagnostic pitfalls, and contemporary management strategies. By synthesizing current evidence, we aim to provide clinicians with practical insights to guide decision-making in the era of advanced cardiac imaging and percutaneous interventions.