The hook effect of an immunoassay results in a series of pediatric patients with elevated total immunoglobulin E: implications for dilution protocols and method comparison

Clin Chem Lab Med. 2025 Dec 1. doi: 10.1515/cclm-2025-1492. Online ahead of print.

Authors

Oleg Melnichuk¹, Ekaterina Brzhozovskaya¹, Maria Borodina¹, Nikolay Mayanskiy¹

Affiliation

¹ 64882 Pirogov Russian National Research Medical University , Moscow, Russia.

PMID: 41316679
DOI: 10.1515/cclm-2025-1492

No abstract available

Keywords: cobas e411; hook effect; immunoassay interference; maglumi 2000 plus; total immunoglobulin E.

Publication types

Letter