Coronary Microvascular Dysfunction and Premature Ventricular Contractions in Patients With Stable Angina

Ann-Kathrin Kahle; Bahram Wafaisade; Fares-Alexander Alken; Katharina Scherschel; Ernan Zhu; Nicola A Cicco; Alexandru Gabriel Bejinariu; Florian Bönner; Malte Kelm; Mareike Cramer; Christian Meyer

doi:10.1001/jamanetworkopen.2025.46595

Coronary Microvascular Dysfunction and Premature Ventricular Contractions in Patients With Stable Angina

JAMA Netw Open. 2025 Dec 1;8(12):e2546595. doi: 10.1001/jamanetworkopen.2025.46595.

Authors

Ann-Kathrin Kahle^{1

2}, Bahram Wafaisade¹, Fares-Alexander Alken¹, Katharina Scherschel^{1

3

4}, Ernan Zhu¹, Nicola A Cicco¹, Alexandru Gabriel Bejinariu², Florian Bönner⁵, Malte Kelm^{2

4}, Mareike Cramer², Christian Meyer^{1

3}

Affiliations

¹ Division of Cardiology, Angiology, Intensive Care Medicine, EVK Düsseldorf, cNEP, Cardiac Neuro- and Electrophysiology Research Consortium, Düsseldorf, Germany.
² Department of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.
³ Institute of Neural and Sensory Physiology, cNEP, Cardiac Neuro- and Electrophysiology Research Consortium, Heinrich Heine University Düsseldorf, Medical Faculty, Düsseldorf, Germany.
⁴ Cardiovascular Research Institute Düsseldorf, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.
⁵ Department of Cardiology, Vascular Medicine and Pulmonology, Hospital Düren, Düren, Germany.

No abstract available

Plain language summary

This case-control study examines associations of coronary microvascular dysfunction (CMD) with occurrence of premature ventricular contractions among patients with stable angina or equivalent symptoms.