Non-obstructive myocardial stunning is characterized by transient myocardial contractile dysfunction despite preserved coronary perfusion. Although increasingly recognized, it remains a diagnostic and therapeutic challenge in cardiology. This review synthesizes current insights into reversible cardiomyopathies, explores the potential of antimetabolic and anti-ischemic agents in their management, and highlights emerging therapeutic avenues. Greater understanding of these mechanisms may improve patient outcomes in this underexplored area.
Keywords: Anti-ischemic agents; Energy metabolism; Neurohumoral mechanisms; Non-obstructive stunning; Oxidative stress; İnflammation.
© 2025. The Author(s).