The 1927 nm Thulium laser has emerged as a promising tool for the treatment of dermatological conditions. This systematic review aimed to analyze the efficacy and applicability of this technology. A total of 17 studies were included, involving 448 participants with various dermatological disorders. The results indicated that the 1927 nm laser promoted improvements in skin texture, pigmentation reduction, and scar appearance, with an acceptable of safety profile. On average, treatment protocols included three sessions at monthly intervals and a follow-up of 120 days. Adverse events were mild and transient, although relapses were observed in cases of melasma. There was considerable variability in treatment parameters across studies, and most of them presented a moderate to high risk of bias. Therefore, future research is needed to standardize clinical protocols and confirm long-term effects. Nevertheless, the 1927 nm laser stands out as a valuable dermatological therapeutic resource with the potential to enhance clinical outcomes.
Keywords: 1927nm thulium laser; Acne scars; Dermatological conditions; Laser therapy; Melasma treatment; Pigmentation disorders; Skin rejuvenation; Systematic review.
© 2025. The Author(s), under exclusive licence to Springer-Verlag London Ltd., part of Springer Nature.