Glioma cells achieve malignant progression by fusion with macrophages to gain high SLC7A5 expression

J Neurooncol. 2025 Dec 16;176(2):126. doi: 10.1007/s11060-025-05382-6.

Yuedong Hu¹, Fusheng Liu^{2

3

4}, Ruifang Mi^{5

6}

¹ Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100070, China.
² Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100070, China. liufushengs@hotmail.com.
³ Neurosurgical Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, China. liufushengs@hotmail.com.
⁴ Brain Tumor Research Center, Beijing Neurosurgical Institute, Capital Medical University, 119 Fanyang Road, Fengtai District, Beijing, 100070, P.R. China. liufushengs@hotmail.com.
⁵ Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100070, China. miruifang2013@hotmail.com.
⁶ Brain Tumor Research Center, Beijing Neurosurgical Institute, Capital Medical University, 119 Fanyang Road, Fengtai District, Beijing, 100070, P.R. China. miruifang2013@hotmail.com.

No abstract available

Keywords: SLC7A5; Cell fusion; Glioma; JPH203; Macrophage; Malignant progression.

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