Effects of long-term oral administration of isosorbide dinitrate on the antianginal response to nitroglycerin. Absence of nitrate cross-tolerance and self-tolerance shown by exercise testing

Am J Cardiol. 1978 Jan;41(1):82-7. doi: 10.1016/0002-9149(78)90136-4.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Administration, Oral
  • Angina Pectoris / drug therapy*
  • Blood Pressure / drug effects
  • Delayed-Action Preparations
  • Drug Tolerance
  • Electrocardiography / methods
  • Exercise Test*
  • Female
  • Heart Rate / drug effects
  • Humans
  • Isosorbide Dinitrate / administration & dosage*
  • Isosorbide Dinitrate / pharmacology
  • Isosorbide Dinitrate / therapeutic use
  • Long-Term Care
  • Male
  • Middle Aged
  • Nitroglycerin / pharmacology
  • Nitroglycerin / therapeutic use*
  • Oxygen Consumption / drug effects
  • Time Factors

Substances

  • Delayed-Action Preparations
  • Nitroglycerin
  • Isosorbide Dinitrate