Fertility preservation in gynecologic oncology: evaluating knowledge, practices, and barriers among French healthcare providers

Int J Gynecol Cancer. 2026 Jan;36(1):102782. doi: 10.1016/j.ijgc.2025.102782. Epub 2025 Nov 5.

Abstract

Objective: To assess the knowledge, practices, and referral patterns of health care professionals and fertility preservation specialists regarding fertility preservation in gynecologic oncology in France.

Methods: In this cross sectional study, an electronic questionnaire was distributed between June 2023 and January 2024 to health care professionals in metropolitan and overseas territories. It included sections on demographics, fertility preservation practices, and technical knowledge, with tailored sections for physicians who are specialists and non-specialists in reproductive medicine.

Results: Sixty-four professionals participated (mean experience: 12 years); 65.6% (42/64) were gynecologic surgeons, and 18.8% (12/64) were specialists in reproductive medicine. Among non-specialists (52/64), 82.7% (43/52) routinely discussed fertility with patients of childbearing age, and 94.2% (49/52) had referred patients for fertility preservation. The mean knowledge score was 1.4/6. Only 23.1% (12/52) reported having written materials for patients, and 65.4% (34/52) indicated that no fertility specialist was present at multidisciplinary meetings. All reproductive medicine specialists (n = 12) reported access to oocyte and ovarian tissue cryopreservation, but 83.3% (10/12) believed patients were under-referred. They emphasized the need for systematic discussions of fertility preservation in multidisciplinary settings and highlighted risks associated with ovarian stimulation and tissue reimplantation. The upper age limit for oocyte cryopreservation was generally under 40 years. Pregnancy outcomes following fertility preservation were limited, primarily in cases of borderline ovarian tumors.

Conclusions: Fertility preservation is recognized as a critical component of gynecologic oncology care, but significant gaps remain in knowledge, referrals, and integration into multidisciplinary care. Strengthening collaboration between oncology and fertility teams, standardizing care pathways, and enhancing education for health care providers are essential steps to improving access and outcomes for patients.

Keywords: Cervical Cancer; Endometrial Cancer; Fertility Preservation; Ovarian Cancer; Pregnancy.

MeSH terms

  • Adult
  • Cross-Sectional Studies
  • Female
  • Fertility Preservation* / methods
  • Fertility Preservation* / statistics & numerical data
  • France
  • Genital Neoplasms, Female* / therapy
  • Gynecology
  • Health Knowledge, Attitudes, Practice*
  • Health Personnel* / statistics & numerical data
  • Humans
  • Male
  • Middle Aged
  • Practice Patterns, Physicians'* / statistics & numerical data
  • Surveys and Questionnaires