The N-hydroxylation of phentermine (2-methyl-2-amino-1-phenylpropane). Properties of the enzyme system

Drug Metab Dispos. 1974 Jan-Feb;2(1):1-8.
No abstract available

MeSH terms

  • Amines / pharmacology
  • Animals
  • Carbon Monoxide / pharmacology
  • Chromatography, Gas
  • Dealkylation
  • Guinea Pigs
  • Hydroxylation
  • In Vitro Techniques
  • Kinetics
  • Mass Spectrometry
  • Microsomes, Liver / metabolism
  • Niacinamide / pharmacology
  • Oximes / analysis
  • Phentermine / metabolism*
  • Proadifen / pharmacology
  • Rabbits
  • Rats
  • Species Specificity
  • Time Factors

Substances

  • Amines
  • Oximes
  • Niacinamide
  • Carbon Monoxide
  • Proadifen
  • Phentermine