Detection of clonal hematopoiesis of indeterminate potential via genome or exome sequencing underestimates disease associations
J Clin Invest
.
2026 Jan 13:e198861.
doi: 10.1172/JCI198861.
Online ahead of print.
Authors
Robert Corty
1
,
Yash Pershad
1
,
J Brett Heimlich
1
,
Caitlyn Vlasschaert
2
,
Leo Luo
3
,
Taralynn Mack
4
,
Kaushik Amancherla
1
,
Cassianne Robinson-Cohen
1
,
Michael Savona
1
,
Alexander G Bick
1
Affiliations
1
Department of Internal Medicine, Vanderbilt University Medical Center, Nashville, United States of America.
2
Department of Internal Medicine, Queen's University, Kingston, Canada.
3
Department of Radiation Oncology, Vanderbilt University Medical Center, Nashville, United States of America.
4
University of Washington, Seattle, United States of America.
PMID:
41528807
DOI:
10.1172/JCI198861
No abstract available
Keywords:
Aging; Epidemiology; Genetics; Hematopoietic stem cells.