Sulfisoxazole as chemoprophylaxis for recurrent otitis media. A double-blind crossover study in pediatric practice

N Engl J Med. 1974 Sep 26;291(13):664-7. doi: 10.1056/NEJM197409262911307.
No abstract available

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Acute Disease
  • Administration, Oral
  • Child
  • Child, Preschool
  • Clinical Trials as Topic
  • Cooperative Behavior
  • Female
  • Follow-Up Studies
  • Haemophilus influenzae / isolation & purification
  • Humans
  • Infant
  • Male
  • Nasopharynx / microbiology
  • Otitis Media / epidemiology
  • Otitis Media / microbiology
  • Otitis Media / prevention & control*
  • Placebos
  • Recurrence
  • Streptococcus / isolation & purification
  • Streptococcus pneumoniae / isolation & purification
  • Sulfisoxazole / administration & dosage
  • Sulfisoxazole / therapeutic use*

Substances

  • Placebos
  • Sulfisoxazole