Molecular Characterization of a Complex PDGFRB Structural Variation in Infantile Myofibroma With Complete Response to Imatinib

JCO Precis Oncol. 2026 Jan:10:e2500943. doi: 10.1200/PO-25-00943. Epub 2026 Jan 14.

Wynn E Bastianelli¹, Jinhua Wu², Mian Umair Ahsan^{3

4

5}, Ava M Szepessy¹, Jeffery Schubert², Naomi J Balamuth^{1

4}, Joe Chan^{3

4

5}, Elizabeth H Denenberg², Minjie Luo^{2

6}, Avrum N Pollock^{4

7}, Pierre A Russo², Karleena Rybacki^{3

8}, Feng Xu², Yiming Zhong^{2

6}, Lea F Surrey^{2

6}, Kai Wang^{3

6}, Theodore W Laetsch^{1

4}, Marilyn M Li^{2

4

6}

¹ Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA.
² Division of Genomic Diagnostics, Children's Hospital of Philadelphia, Philadelphia, PA.
³ Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA.
⁴ Department of Pediatrics, The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
⁵ Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA.
⁶ Department of Pathology and Laboratory Medicine, The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
⁷ Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA.
⁸ Department of Bioengineering, University of Pennsylvania, Philadelphia, PA.

No abstract available

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