The role of γ-secretase in familial hidradenitis suppurativa: Implications for pathogenesis and targeted therapy
JAAD Case Rep
.
2025 Nov 19:68:62-63.
doi: 10.1016/j.jdcr.2025.11.010.
eCollection 2026 Feb.
Authors
Bethel Desta
1
,
Ekaterina Korytnikova
2
,
Madeleine Tessier-Kay
2
,
Tim Klufas
2
,
Jun Lu
2
,
Akua Sarfo
2
,
Albert E Zhou
2
Affiliations
1
University of Texas Medical Branch, John Sealy School of Medicine, Galveston, Texas.
2
Department of Dermatology, University of Connecticut School of Medicine, Farmington, Connecticut.
PMID:
41537012
PMCID:
PMC12796519
DOI:
10.1016/j.jdcr.2025.11.010
No abstract available
Keywords:
HS; familial HS; gamma-secretase; nirogacestat; pathogenesis; subtypes; therapies.
Publication types
Letter