The role of intestinal microflora in prehabilitation for colorectal cancer surgery - systematic review

Pol Przegl Chir. 2025 Sep 1;97(6):64-68. doi: 10.5604/01.3001.0055.2587.

Abstract

Colorectal cancer (CRC) is a global health issue that frequently necessitates surgical treatment. Prehabilitation, a strategy designed to enhance patients' health status prior to surgery, has been recognized as an effective approach to improve surgical outcomes. Probiotics, celebrated for their positive impact on gut health, have been identified as a potential component of prehabilitation regimens for CRC patients. Nonetheless, the evidence supporting their efficacy in this setting is not yet definitive. This systematic review is intended to assess the role of probiotics in the prehabilitation of patients scheduled for colorectal cancer surgery.

Keywords: colon cancer; intestinal microflora; surgery.

Publication types

  • Systematic Review

MeSH terms

  • Colorectal Neoplasms* / surgery
  • Female
  • Gastrointestinal Microbiome*
  • Humans
  • Male
  • Preoperative Care* / methods
  • Probiotics* / therapeutic use