Reassessing AXP depletion due to inherited deficiency of adenosine deaminase 1

Pawan Bali; Susan J Kelly; Ines Santisteban; Francisco X Arredondo-Vega; Kees Frelinger; Rishi Rampersad; Teresa K Tarrant; Michael S Hershfield

doi:10.1016/j.jaci.2025.12.1004

Reassessing AXP depletion due to inherited deficiency of adenosine deaminase 1

J Allergy Clin Immunol. 2026 Apr;157(4):993-995. doi: 10.1016/j.jaci.2025.12.1004. Epub 2026 Jan 20.

Authors

Pawan Bali¹, Susan J Kelly¹, Ines Santisteban¹, Francisco X Arredondo-Vega¹, Kees Frelinger¹, Rishi Rampersad¹, Teresa K Tarrant², Michael S Hershfield³

Affiliations

¹ Department of Medicine, Division of Rheumatology and Immunology, Duke University School of Medicine, Durham, NC.
² Department of Medicine, Division of Rheumatology and Immunology, Duke University School of Medicine, Durham, NC; Department of Medicine, Veterans Affairs Medical Center, Durham, NC.
³ Department of Medicine, Division of Rheumatology and Immunology, Duke University School of Medicine, Durham, NC; Department of Biochemistry, Duke University School of Medicine, Durham, NC. Electronic address: michael.hershfield@duke.edu.

PMID: 41563156
DOI: 10.1016/j.jaci.2025.12.1004

No abstract available

Keywords: Adenosine deaminase deficiency; adenine deoxyribonucleotides; adenine ribonucleotides; enzyme replacement therapy; severe combined immune deficiency.

Publication types

Letter