In AF with drug-eluting stent for ≥1 y, NOACs were noninferior to NOAC + clopidogrel for a composite of adverse clinical events at 1 y

Ann Intern Med. 2026 Feb;179(2):JC15. doi: 10.7326/ANNALS-25-05478-JC. Epub 2026 Feb 3.

Abstract

GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text].

MeSH terms

  • Anticoagulants* / adverse effects
  • Anticoagulants* / therapeutic use
  • Atrial Fibrillation* / complications
  • Atrial Fibrillation* / drug therapy
  • Clopidogrel* / adverse effects
  • Clopidogrel* / therapeutic use
  • Drug Therapy, Combination
  • Drug-Eluting Stents*
  • Humans
  • Platelet Aggregation Inhibitors* / adverse effects
  • Platelet Aggregation Inhibitors* / therapeutic use

Substances

  • Clopidogrel
  • Platelet Aggregation Inhibitors
  • Anticoagulants