Adenosine: potential target as rapid-acting antidepressants

Purinergic Signal. 2026 Feb 4;22(1):17. doi: 10.1007/s11302-026-10133-x.

Jia-Jia Li¹, Yong Tang^{2

3}, Peter Illes^{4

5

6}

¹ International Joint Research Centre on Purinergic Signalling, School of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
² International Joint Research Centre on Purinergic Signalling, School of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China. tangyong@cdutcm.edu.cn.
³ School of Health and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu, China. tangyong@cdutcm.edu.cn.
⁴ International Joint Research Centre on Purinergic Signalling, School of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China. peter.illes@medizin.uni-leipzig.de.
⁵ School of Health and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu, China. peter.illes@medizin.uni-leipzig.de.
⁶ Rudolf Boehm Institute for Pharmacology and Toxicology, University of Leipzig, Leipzig, Germany. peter.illes@medizin.uni-leipzig.de.

No abstract available

Keywords: Adenosine; ECT; Ketamine; Rapid-acting antidepressant; mPFC.

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