Immunological studies of eosinophilic gastro-enteritis and treatment with disodium cromoglycate and beclomethasone dipropionate

S Afr Med J. 1977 Nov 12;52(21):838-41.


A 45-year-old woman with intestinal malabsorption due to eosinophilic gastro-enteritis was found to have markedly fluctuating total serum IgE levels with a positive intradermal skin test and a positive radio-allergosorbent test to milk antigen. No organ-specific or non-organ-specific auto-antibodies were detected in the patient's serum, and her complement profile was normal. Low doses of disodium cromoglycate failed to improve intestinal absorption, whereas a 16-day course of a corticosteroid, beclomethasone dipropionate 3 mg daily, improved D-xylose and carotene absorption without suppressing the hypothalamic-pituitary-adrenal axis.

Publication types

  • Case Reports

MeSH terms

  • Beclomethasone / therapeutic use*
  • Cromolyn Sodium / therapeutic use*
  • Eosinophils*
  • Female
  • Food Hypersensitivity / complications
  • Gastroenteritis / complications
  • Gastroenteritis / drug therapy*
  • Gastroenteritis / immunology
  • Humans
  • Immunoglobulin E / analysis
  • Middle Aged


  • Immunoglobulin E
  • Beclomethasone
  • Cromolyn Sodium