Mitochondrial dysfunction in hypertension: mechanistic pathways and therapeutic implications

Jiao Tian; Lin Yi; Yuyuan Lu; Yushun Kou; Lingna Zhang; Penghui Jin; Xiaoke Wang; Tao Wu; Xin Yang; Yiyuan Wang; Ruiling Ma

doi:10.1007/s10142-025-01813-9

Mitochondrial dysfunction in hypertension: mechanistic pathways and therapeutic implications

Funct Integr Genomics. 2026 Feb 9;26(1):40. doi: 10.1007/s10142-025-01813-9.

Authors

Jiao Tian^#¹, Lin Yi^#², Yuyuan Lu¹, Yushun Kou¹, Lingna Zhang¹, Penghui Jin³, Xiaoke Wang³, Tao Wu¹, Xin Yang³, Yiyuan Wang¹, Ruiling Ma¹

Affiliations

¹ School of Traditional Chinese and Western Medicine, Gansu University of Chinese Medicine, Lanzhou, Gansu Province, 730000, China.
² School of Traditional Chinese and Western Medicine, Gansu University of Chinese Medicine, Lanzhou, Gansu Province, 730000, China. yxxxlyyy@163.com.
³ First School of Clinical Medicine, Gansu University of Chinese Medicine, Lanzhou, 730000, Gansu Province, China.

^# Contributed equally.

PMID: 41656396
DOI: 10.1007/s10142-025-01813-9

No abstract available

Keywords: Ca2+ handling; Chinese herb extracts; Fusion and fission; Hypertension; Mitochondria; Mitophagy; Oxidative stress; Uncoupling; Western substances compounds.

Publication types

Review

Publication types

Grants and funding