Copper and inflammation

Agents Actions. 1978 Jan;8(1-2):85-90. doi: 10.1007/BF01972407.

Abstract

Bonta, Sorenson and others have shown that Cu(II) derivatives are effective anti-inflammatory agents. Some chemical and pharmacological properties of Cu(I) and metallic Cu are discussed. Thio complexes of Cu(I) were prepared and shown to be useful anti-inflammatory agents in rats. Hypotheses are stated concerning the possible therapeutic value of copper in its various oxidation states.

Publication types

  • Historical Article

MeSH terms

  • Animals
  • Anti-Inflammatory Agents* / history
  • Anti-Inflammatory Agents, Non-Steroidal
  • Arthritis, Experimental / drug therapy
  • Chemistry
  • Copper / history
  • Copper / pharmacology*
  • Copper / toxicity
  • Female
  • Gold / pharmacology
  • Gold Sodium Thiomalate / chemical synthesis
  • History, Ancient
  • Irritants
  • Male
  • Rats
  • Thiomalates / chemical synthesis

Substances

  • Anti-Inflammatory Agents
  • Anti-Inflammatory Agents, Non-Steroidal
  • Irritants
  • Thiomalates
  • Gold Sodium Thiomalate
  • Gold
  • Copper