Beyond the RAAS: The Search for Novel Antihypertensive Therapies: A Needle in the Haystack?

J Am Coll Cardiol. 2026 Feb 3:S0735-1097(25)10581-0. doi: 10.1016/j.jacc.2025.12.049. Online ahead of print.

Authors

Reinhold Kreutz¹, Mattias Brunström²

Affiliations

¹ Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Clinical Pharmacology and Toxicology, Berlin, Germany. Electronic address: reinhold.kreutz@charite.de.
² Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.

PMID: 41670562
DOI: 10.1016/j.jacc.2025.12.049

No abstract available

Keywords: antihypertensive therapy; blood pressure; drug development; hypertension; natriuretic peptide receptor 1.

Publication types

Editorial