Pepsinogen D. A fourth proteolytic zymogen from pig gastric mucosa

Biochem J. 1967 Sep;104(3):735-41. doi: 10.1042/bj1040735.

Abstract

Methods are described for the isolation and purification of pepsinogen D, a minor zymogen occurring to the extent of about 5% of the potential proteolytic activity in neutral extracts of the pig gastric mucosa. The physical and chemical properties of this zymogen indicate that it is very similar to, if not identical with, dephosphopepsinogen.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Cattle
  • Chromatography
  • Chymotrypsin / metabolism
  • Dialysis
  • Electrophoresis
  • Enzyme Precursors / analysis*
  • Gastric Mucosa / enzymology*
  • Hemoglobins / metabolism
  • Milk / drug effects
  • Pepsin A*
  • Peptide Hydrolases / metabolism
  • Staining and Labeling

Substances

  • Enzyme Precursors
  • Hemoglobins
  • Peptide Hydrolases
  • Chymotrypsin
  • Pepsin A