Keeping cells fit

Science. 2026 Feb 12;391(6786):657-658. doi: 10.1126/science.aee7910. Epub 2026 Feb 12.

Authors

Xavier Rambout^{1

2}, Lynne E Maquat^{1

2}

Affiliations

¹ Department of Biochemistry & Biophysics, School of Medicine and Dentistry, University of Rochester, Rochester, NY, USA.
² Center for RNA Biology, University of Rochester, Rochester, NY, USA.

PMID: 41678632
DOI: 10.1126/science.aee7910

Abstract

Fragments of aberrant cytoplasmic mRNA pair with nuclear RNAs to augment transcription.

MeSH terms

Animals
Cell Nucleus / genetics
Cell Nucleus / metabolism
Cytoplasm / genetics
Cytoplasm / metabolism
Humans
RNA Stability*
RNA, Messenger* / genetics
RNA, Messenger* / metabolism
RNA, Nuclear* / genetics
RNA, Nuclear* / metabolism
Transcription, Genetic*

Substances

RNA, Messenger
RNA, Nuclear