Unveiling the whole-brain impact of diffuse midline glioma: cortical morphological remodeling and network alterations driven by H3 K27 mutation

Neuroradiology. 2026 Feb 19. doi: 10.1007/s00234-026-03940-x. Online ahead of print.

Di Chen¹, Simin Zhang^#^{1

2}, Dian Zhang¹, Yuan Yang³, Xibiao Yang¹, Yujiao Deng¹, Ni Chen⁴, Yanhui Liu³, Qiang Yue⁵

¹ Department of Radiology, West China Hospital of Sichuan University, Chengdu, China.
² Huaxi MR Research Center, West China Hospital of Sichuan University, Chengdu, China.
³ Department of Pathology, West China Hospital of Sichuan University, Chengdu, China.
⁴ Department of Neurosurgery, West China Hospital of Sichuan University, Chengdu, China.
⁵ Department of Radiology, West China Hospital of Sichuan University, Chengdu, China. scu_yq@163.com.

^# Contributed equally.

No abstract available

Keywords: Cortical thickness; Diffuse midline glioma; H3 K27; Local gyrification index; Structural covariance network.

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