Polycystic ovary syndrome: An update on diagnosis and management

Nayoung Sung; Jawaria Amir; Ula Abed Alwahab; Tommaso Falcone

doi:10.3949/ccjm.93a.25090

Polycystic ovary syndrome: An update on diagnosis and management

Cleve Clin J Med. 2026 Mar 2;93(3):176-183. doi: 10.3949/ccjm.93a.25090.

Authors

Nayoung Sung¹, Jawaria Amir², Ula Abed Alwahab³, Tommaso Falcone⁴

Affiliations

¹ Specialized Women's Health, Obstetrics & Gynecology Institute, Cleveland Clinic, Cleveland, OH.
² Obstetrics & Gynecology Institute, Cleveland Clinic, Cleveland, OH.
³ Endocrinology & Metabolism Institute/Administration, Cleveland Clinic, Cleveland, OH; Clinical Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH abedalu@ccf.org.
⁴ Obstetrics & Gynecology Institute, Cleveland Clinic, Cleveland, OH; Academic Department Chair, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.

PMID: 41771679
DOI: 10.3949/ccjm.93a.25090

Abstract

Polycystic ovary syndrome (PCOS) is a common but complex heterogeneous endocrine disorder characterized by androgen excess, insulin resistance, and ovulatory dysfunction, presenting challenges in diagnosis and management. This review provides an overview of PCOS, incorporating key updates from the 2023 international evidence-based guideline. We aim to enhance understanding of PCOS and improve individualized and evidence-based patient care.

Publication types

Review

MeSH terms

Disease Management
Female
Humans
Insulin Resistance
Polycystic Ovary Syndrome* / diagnosis
Polycystic Ovary Syndrome* / therapy