Social drivers of health and perioperative outcomes: Identifying domains and barriers with significant impact

Am J Surg. 2026 Jun:256:116890. doi: 10.1016/j.amjsurg.2026.116890. Epub 2026 Feb 28.

Abstract

Objectives: This retrospective cohort of patients undergoing surgery from 2019 to 2023 evaluated the association between individual-level social drivers of health (SDoH) and postoperative outcomes (length of stay, 30-day mortality, 30-day readmission).

Methods: Patients from a multi-site health system who completed a SDoH questionnaire were categorized as high-risk or not high-risk across five SDoH domains (e.g., financial resources) and were stratified into 3 surgical cohorts (elective outpatient, inpatient and emergency surgery). Regression models, adjusted for potential confounders, assessed the association between SDoH and postoperative outcomes.

Results: Among 297,723 patients, 74% completed the SDoH questionnaire. High-risk transportation need was associated with higher unplanned 30-day readmission for all cohorts; for elective surgeries, high-risk transportation was also associated with higher mortality. The other SDoH domains were inconsistently associated with postoperative outcomes.

Conclusions: Individual-level SDoH, particularly transportation needs and financial strain, are linked to adverse postoperative surgical outcomes. Systematic SDoH interventions are crucial to addressing healthcare disparities.

Keywords: Disparities; Elective surgery; Emergency surgery; Perioperative outcomes; Social determinants of health.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Aged
  • Elective Surgical Procedures
  • Female
  • Healthcare Disparities*
  • Humans
  • Length of Stay / statistics & numerical data
  • Male
  • Middle Aged
  • Patient Readmission / statistics & numerical data
  • Postoperative Complications* / epidemiology
  • Retrospective Studies
  • Social Determinants of Health*
  • Surgical Procedures, Operative* / mortality
  • Surveys and Questionnaires