We evaluated the effectiveness of a community research partnership focused on improving severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing for New York City residents during the pandemic. We employed interviews, a focus group, and a survey to evaluate partnership characteristics, engagement, and future collaboration. Qualitative analysis revealed five core themes: committee identity, collective goals, information sharing, adaptability, and trust. The findings highlight the importance of flexibility, shared goals, diverse representation, open communication, and trust in effective multisector community health partnerships. (Am J Public Health. 2026;116(4):431-436. https://doi.org/10.2105/AJPH.2025.308358).