Evidence-Based Steps to Mitigate Bacterial Contamination

Clin Plast Surg. 2026 Apr;53(2):203-209. doi: 10.1016/j.cps.2025.11.006. Epub 2025 Dec 13.

Abstract

Capsular contracture, the most common complication in breast implant surgery, is primarily driven by bacterial biofilm formation. Risk is influenced by surgical factors such as incision choice, implant placement, and sterility. Textured implants do not reduce contracture and may increase complications, including breast implant-associated anaplastic large cell lymphoma. Evidence-based strategies-most notably the 14 point plan, betadine-based antimicrobial irrigations, meticulous surgical technique, and structured postoperative care-have reduced contracture rates from up to 50% historically to under 1% in modern practice. Comprehensive management with capsulectomy, site change, and adjuncts further optimizes long-term outcomes and patient satisfaction.

Keywords: 14 point plan; BIA-ALCL; Bacterial contamination; Breast implant; Capsular contracture; Device associated infection; SCCA; Surgical technique.

Publication types

  • Review

MeSH terms

  • Biofilms
  • Breast Implantation* / adverse effects
  • Breast Implantation* / methods
  • Breast Implants* / adverse effects
  • Breast Implants* / microbiology
  • Evidence-Based Medicine
  • Female
  • Humans
  • Implant Capsular Contracture* / etiology
  • Implant Capsular Contracture* / microbiology
  • Implant Capsular Contracture* / prevention & control
  • Prosthesis-Related Infections* / prevention & control
  • Surgical Wound Infection* / prevention & control