Identification of the Novel HLA-DPB1*04:02:36 Allele, a Synonymous Variant of HLA-DPB1*04:02:01:02

HLA. 2026 Mar;107(3):e70664. doi: 10.1111/tan.70664.

Abstract

HLA-DPB1*04:02:36 differs from HLA-DPB1*04:02:01:02 by a synonymous CAG → CAA substitution in codon 62 in exon 2.

Keywords: HLA‐DPB1*04:02:36; NGS; bone marrow transplantation; new allele.

MeSH terms

  • Alleles*
  • Base Sequence
  • Codon / chemistry
  • Exons*
  • HLA-DP beta-Chains* / genetics
  • HLA-DP beta-Chains* / immunology
  • Histocompatibility Testing
  • Humans
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Silent Mutation*

Substances

  • HLA-DP beta-Chains
  • HLA-DPB1 antigen
  • Codon