Efficient Transgene-Free Multiplexed Germline Editing via Viral Delivery of an Engineered TnpB

Plant Biotechnol J. 2026 Jun;24(6):4358-4360. doi: 10.1111/pbi.70644. Epub 2026 Mar 17.

Trevor Weiss¹, Maris Kamalu¹, Honglue Shi^{2

3

4}, Gabriel Wirnowski¹, Alice Ingelsson¹, Jasmine Amerasekera¹, Kamakshi Vohra^{2

4}, Marena I Trinidad^{2

5}, Zheng Li¹, Emily Freitas¹, Noah Steinmetz¹, Charlie Ambrose¹, Kerry Chen¹, Jennifer A Doudna^{2

3

4}, Steven E Jacobsen^{1

6}

¹ Department of Molecular, Cell and Developmental Biology, University of California at Los Angeles, Los Angeles, California, USA.
² Innovative Genomics Institute, University of California, Berkeley, California, USA.
³ Howard Hughes Medical Institute, University of California, Berkeley, California, USA.
⁴ California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, California, USA.
⁵ University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, University of California, Berkeley, California, USA.
⁶ Howard Hughes Medical Institute, University of California at Los Angeles, Los Angeles, California, USA.

No abstract available

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