Trends in Coronavirus Disease 2019 Mortality Within a US Academic Health System, 2020-2025

Open Forum Infect Dis. 2026 Mar 14;13(3):ofag138. doi: 10.1093/ofid/ofag138. eCollection 2026 Mar.

Abstract

Coronavirus disease 2019 (COVID-19) was initially associated with higher mortality than other respiratory viruses. We assessed trends in mortality following a positive COVID-19 test within a single academic health system. Among individuals with COVID-19, 30-day crude and adjusted mortality rates have decreased but remain numerically similar to higher than influenza.

Keywords: coronavirus disease 2019 (COVID-19).