Immunoconglutinin and Complement Changes in Children With Acute Nephritis

Clin Exp Immunol. 1969 Dec;5(6):557-66.

Abstract

Immunoconglutinin and electrophoretically altered forms of complement are detectable only after the fall in complement levels in acute nephritis, and may occur even when the fall is not noted. The delay between the postulated initiating streptococcal infection and the development of immunoconglutinin is longer than would be expected. The immunopathological significance of these findings is discussed.

MeSH terms

  • Acute Disease
  • Age Factors
  • Autoantibodies / analysis*
  • Beta-Globulins / analysis
  • Child
  • Child, Preschool
  • Complement System Proteins / analysis*
  • Coombs Test
  • Female
  • Hemolysis
  • Humans
  • Immunodiffusion
  • Immunoelectrophoresis
  • Male
  • Nephritis / etiology
  • Nephritis / immunology*
  • Streptococcal Infections / complications

Substances

  • Autoantibodies
  • Beta-Globulins
  • Complement System Proteins