In patients with shock, early recognition and timely initiation of appropriate management critically impacts patient outcomes. Currently prevalent approaches to shock in the emergency department have two major limitations: reliance hypotension as a defining criterion, and confining evaluation and management within a four-category framework. This approach risks oversimplifying a complex, dynamic physiologic state by emphasizing diagnostic labeling over a mechanistic approach to circulatory failure. This article reframes shock as a continuum progressing from physiologic stress to tissue hypoperfusion resulting from a failure of forward flow, which is conceptualized here as the sum of competing forward, backward, and external pressures. Approaching hemodynamics through this lens offers a mental model of shock that balances physiologic sophistication with clinical utility in order to equip frontline clinicians with a more robust toolset for evaluation and management of complex shock patients.
Keywords: Hypoperfusion; Pressure interfaces; Shock.
Copyright © 2025 Elsevier Inc. All rights reserved.