Helicobacter felis-Associated Acute Gastric Mucosal Lesion: Ultrastructure by Low-Vacuum Scanning Electron Microscopy

Pathol Int. 2026 Apr;76(4):e70109. doi: 10.1111/pin.70109.

Abstract

This report describes a rare case of acute gastric mucosal lesion associated with H. felis infection. Numerous bacilli were identified within the mucopurulent exudate. The microorganisms were larger, longer, and more tightly coiled than H. pylori. Low vacuum-SEM reveals the spiral microorganisms with characteristic two or three periplasmic fibrils on the surface. RT-PCR detected the presence of H. felis urease B gene.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Female
  • Gastric Mucosa* / microbiology
  • Gastric Mucosa* / pathology
  • Gastric Mucosa* / ultrastructure
  • Helicobacter Infections* / microbiology
  • Helicobacter Infections* / pathology
  • Helicobacter felis* / genetics
  • Helicobacter felis* / isolation & purification
  • Helicobacter felis* / ultrastructure
  • Humans
  • Male
  • Microscopy, Electron, Scanning / methods
  • Middle Aged